Nephrogenic systemic fibrosis: a systemic fibrosing disease resulting from gadolinium exposure.
نویسندگان
چکیده
Nephrogenic systemic fibrosis (NSF) is an iatrogenic fibrosing disorder that primarily affects individuals with chronic kidney disease (CKD) following exposure to gadolinium-based contrast agents (GBCAs) during imaging procedures. NSF is characterised by skin thickening, tethering and hyperpigmentation; flexion contractures of joints; and extracutaneous fibrosis. This article reviews the history, clinical manifestations, epidemiology, histopathology and pathophysiology of this disabling disease.
منابع مشابه
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ورودعنوان ژورنال:
- Best practice & research. Clinical rheumatology
دوره 26 4 شماره
صفحات -
تاریخ انتشار 2012